Slither is the story of a small town invaded by an alien species, turning the residents into monsters.
*Director James Gunn cameos as another teacher at Starla's school.
*People, places and buildings, throughout the film, allude to various late-20th-century monster movies.
*In the script, Jack tells Bill that Brenda is the niece of Randy Flagg. Randall Flagg is the bad guy in several Stephen King novels including "The Stand" (1994).